Mafuta ambiri a Vitamini E

Vitamini E ndi chiyani?

Ndi vitamini wosungunuka m'mafuta, ndipo mankhwala ake a hydrolysis ndi tocopherol, yomwe ndi imodzi mwazofunikira kwambiri za antioxidant. Nthawi zambiri amasungunuka mu zosungunulira za organic monga mafuta ndi ethanol, osasungunuka m'madzi, osasunthika kutentha ndi asidi, osakhazikika ku alkali, kumva mpweya, komanso osamva kutentha, koma ntchito ya vitamini E imachepetsedwa kwambiri yokazinga. Tocopherol imatha kulimbikitsa kutulutsa kwa mahomoni ogonana, kuonjezera mphamvu ndi kuchuluka kwa umuna wamphongo; kuonjezera kuchuluka kwa estrogen yachikazi, kukonza chonde, kupewa kupititsa padera, komanso kungagwiritsidwe ntchito kupewa ndi kuchiza kusabereka kwa amuna, kuyaka, chisanu, kutuluka magazi kwa capillary, menopausal syndrome, ndi kukongola. Posachedwapa, zapezekanso kuti zimatha kulepheretsa lipid peroxidation mu lens ya diso, kukulitsa mitsempha yamagazi, kupititsa patsogolo kayendedwe ka magazi, ndikuletsa kuchitika ndi kukula kwa myopia. Gulu la phenolic hydroxyl pa mphete ya benzene ndi acetylated, ndipo ester imapangidwa ndi hydrolyzed kukhala phenolic hydroxyl gulu kupanga tocopherol. Vitamini E, yemwenso amadziwika kuti tocopherol, makamaka amaphatikizapo mitundu iwiri ya tocopherol ndi tocotrienol, okwana 8 mankhwala, omwe ndi α, β, γ, δ tocopherol ndi α, β, γ, δ tocotrienol. Ndi madzi amafuta agolide kapena opepuka achikasu a viscous, osanunkhiza, okhala ndi fungo lapadera, osasungunuka m'madzi, komanso amasungunuka mosavuta mu zosungunulira za organic monga acetone ndi mafuta. Imakhala yosasunthika ku kuwala kowoneka, imawola pansi pa kuwala kwa ultraviolet, imakhala yokhazikika ku asidi ndi kutentha, ndipo imakhala yosakhazikika m'malo amchere. Ndi antioxidant yofunika yomwe imatha kuchotsa superoxide free radicals, kuletsa lipid peroxidation, ndikuchepetsa kuwonongeka kwa DNA oxidative, kotero imakhala ndi anti-kukalamba.

Chemical katundu:

1. Kusungunuka
Ndimadzimadzi owoneka bwino achikasu kapena achikasu, omwe amasungunuka mosavuta mu anhydrous ethanol acetone, ether petroleum ether, komanso osasungunuka m'madzi.
2. Hydrolysis
Pali magulu a acetylated phenolic hydroxyl pa mphete ya benzene, yomwe imatha kupangidwa ndi hydrolyzed kuti ipange tocopherol yaulere ikatenthedwa munjira za acidic kapena zamchere, motero imagwiritsidwa ntchito ngati chonyansa chapadera.
3. Oxidation:
Ndiwokhazikika kutentha pansi pa mikhalidwe ya anaerobic ndipo sichidzawonongeka ngakhale itatenthedwa kufika ku 200 ° C, koma imakhudzidwa kwambiri ndi mpweya ndipo imatha kukhala oxidized ndi kuwala ndi mpweya. Zomwe zimapangidwa ndi okosijeni ndi a-tocoquinone ndi a-tocopherol dimer.
4. Makhalidwe amayamwidwe a ultraviolet
Pali magulu a phenolic hydroxyl pa mphete ya benzene pamapangidwe a mankhwalawa, omwe amakhala ndi mayamwidwe a ultraviolet. Yankho lake la anhydrous ethanol lili ndi mayamwidwe apamwamba kwambiri pamtunda wa 284nm, ndipo kuyamwa kwake ndi 41.0 ~ 45.0.

Zotsatira:

1. Kuchotsa mawanga, kukongola, kusamalira khungu komanso kuletsa kukalamba
Imakhala ndi antioxidant ndipo imatha kufooketsa ndikulimbana ndi ma free radicals. Ma radicals aulere ndiye chinthu chachikulu chomwe chimayambitsa mawanga, makwinya komanso kukalamba msanga pankhope zathu. Zomwe zili mu VE zimatha kulimbikitsa khungu la collagen, kupititsa patsogolo kayendedwe ka magazi, ndikuchotsa zowonongeka zomwe zimayambitsidwa ndi dzuwa, kuipitsidwa ndi kupsinjika maganizo, kuti athe kulimbana ndi ukalamba kuchokera mkati ndi kunja.

2. Kuteteza mitsempha ya magazi, kupewa thrombosis, ndi kusungunula magazi kuundana
Ikhoza kulepheretsa kutsekeka kwa magazi chifukwa cha kusweka kwa mitsempha ya magazi. Maselo a m'mitsempha yamagazi atasweka, amagwa pansi. Maselo akufa omwe amagwa amakuta mafuta a cholesterol, mafuta, ndi calcium, ndiyeno amakhala chinthu ngati thrombus. Thrombus iyi imayenda m'thupi ndi magazi anu. Ikakumana ndi mphambano, ngati mphambanoyi ndi yopapatiza, thrombus imatha kutsekeka pamalopo, ndipo zimakhala zosavuta kukhala ndi cerebral infarction, myocardial infarction, ndi sitiroko. Kwa thrombus yomwe yapangidwa kale, VE ikhoza kuyisungunula. VE ndi anticoagulant yotetezeka kwambiri, koma ilibe zotsatira zoyipa za anticoagulants.

3. Pewani kuchepa kwa magazi m'thupi ndi jaundice chifukwa cha kuphulika kwa maselo ofiira a magazi
Maselo ofiira amwazi amakhala ndi moyo wa masiku 120. Pamene poizoni m'thupi awonjezeka, adzafupikitsidwa kwambiri. Maselo ofiira a m’magazi akang’ambika msanga, ngati sanawoledwe ndi michere ya m’thupi ndipo vitamini B satengedwa mokwanira, maselo ofiira ambiri amafa, zomwe zimabweretsa kuchepa kwa magazi m’thupi ndi jaundice. Ndiponso, pamene mwana wosabadwayo akukula m’thupi la mayi, chiŵindi chimagwira ntchito mopanda ungwiro. Mayi akakhala ndi pakati, kudya kunja ndikusowa vitamini E, mwana wosabadwayo adzakhala hypoxic ndi jaundice akabadwa.

4. Chepetsani kupanga zipsera
Chiwindi ndi microvessel yayikulu. Selo lililonse lachiwindi limaperekedwa ndi michere ndi mpweya ndi ma microvessels. Ngati E alibe, microcirculation idzakhala yosauka, ndipo mafuta, mapuloteni, ndi mafuta a kolesterolini amawunjikana kuti apangitse chiwindi chamafuta ndi cholesterol yochuluka.
Maselo a chiwindi adzavulala chifukwa cha zakudya zosakwanira. Chiwindi chidzayamba ntchito yodzikonza yokha. Chifukwa cha kuperewera kwa zakudya m'thupi, imakonzedwanso, motero imapanga fibrosis, minofu yamabala imawonekera, ndipo kuuma kumawonekera. Cirrhosis yachiwindi imakhala ndi mafuta ambiri kwa nthawi yayitali chifukwa cha kusayenda bwino kwa chiwindi. Choncho, anthu omwe ali ndi chiwindi chamafuta ayenera kuwonjezera mavitamini. Itha kuteteza lecithin, kugaya ndi kugwiritsa ntchito mafuta ndi mapuloteni, ndikuletsa kuti asakhudzidwe ndi okosijeni. Lecithin imatha kukulitsa michere yomwe yasonkhanitsidwa bwino ndikuwongolera microcirculation yachiwindi. Choncho, matenda enaake a chiwindi akhoza kupewedwa ndi kuchiritsidwa.

5. Kupititsa patsogolo kayendedwe ka magazi,
kuteteza mitsempha ya magazi, ndi kuteteza nembanemba maselo. Osati mitsempha ya magazi yokha, komanso malo ozungulira maso ali ndi ma capillaries wandiweyani. Pamene vitamini E akusowa, elasticity ya mitsempha ya magazi ndi osauka. Mukayang'ana zinthu pafupi, mitsempha yamagazi imalumikizana, koma simatha kutuluka, yomwe imakhala myopia. Mukayang'ana zinthu zakutali, ma capillaries amakula ndipo sangabwerere mmbuyo, zomwe zimakhala strabismus ndi maso opingasa.

6. Anti-oxidation ndi anti-yotupa
Kuchotsa koyipa kwa ma radicals aulere m'thupi, kuchuluka kwa okosijeni, komanso kutupa kosalekeza ndizomwe zimayambitsa kukalamba komanso matenda osiyanasiyana m'thupi la munthu. VE imatha kuchotsa ma radicals aulere, kuchepetsa kuthamanga kwa okosijeni m'thupi, komanso kugwirizana ndi zakudya zina kuti achotse kutupa m'thupi. Itha kulepheretsa cholesterol kukhala oxidized, kusunga thanzi la nembanemba yama cell, ndikuteteza VA kuti ikhale oxidized. Chifukwa chake, imakhudza kwambiri matenda amtima, kuchedwetsa kukalamba, komanso zovuta zosiyanasiyana zotupa komanso matenda osatha.

7. Kupewa matenda a Alzheimer
Matenda a Alzheimer amakhudzana ndi VE m'magazi. Okalamba omwe ali ndi VE wambiri amakhala ndi mwayi wochepa wodwala matenda a Alzheimer's.
Panali kuyesa kokhudza okalamba 232 opitilira zaka 80. Poyamba, palibe amene anali ndi matenda a Alzheimer's, koma m'zaka 6 zotsatira, 57 mwa iwo anapezeka ndi matenda a Alzheimer's. Ofufuzawo adagawa ndikufanizira anthu omwe ali ndi VE yapamwamba komanso yotsika kwambiri m'magazi awo. Zotsatira zake zidawonetsa kuti okalamba omwe ali ndi VE wambiri m'magazi awo anali ndi mwayi wochepa kwambiri wokhala ndi matenda a Alzheimer's. Pambuyo pochotsa zinthu zina, ofufuzawo adapeza kuti chiopsezo cha anthu okalamba omwe ali ndi matenda a Alzheimer's akhoza kuchepetsedwa ndi 45-54% ngati pali VE yapamwamba m'magazi awo.

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YTBIO ikukula m'njira zonse. Tili ndi fakitale yathu, kuyang'anira khalidwe ndi gulu la R&D. Tadzipereka kupatsa makasitomala zabwino kwambiri mafuta ambiri a vitamini E ndi misonkhano. Ndicholinga chathu choyambirira kulola wogula aliyense kusangalala ndi zinthu zapamwamba komanso zathanzi. Ngati muli ndi zosowa kapena mafunso okhudza katundu wathu, chonde omasuka kulankhula nafe ndipo tidzakuyankhani mwamsanga.

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