Luteolin Bulk ufa

Kodi Luteolin Powder ndi chiyani?

Luteolin Bulk ufa (5,7,3',4'-Tetrahydroxyflavone), flavonoid yachilengedwe, yomwe imadziwika kuti luteolin. Kapangidwe kake kakuwonetsedwa pachithunzi 1, ndipo adatengera dzina lake chifukwa chodzipatula ku chomera cha Reseda odorata Linn., cha banja la Resedaceae. Kuchokera pamapangidwe ake, zikuwonekeratu kuti luteolin ndi polyphenolic hydroxyl pawiri ndi osauka lipophilicity. 

Chifukwa cha mphamvu za intermolecular pakati pa magulu a hydroxyl ndi mphamvu yochuluka ya lattice, kusungunuka kwake mu zosungunulira zosiyanasiyana kumakhala kochepa, kumapereka zovuta pokonzekera ndi kugwiritsa ntchito.

NDI:

Ubwino Wathu:

1. Mgwirizano Wogwirizana Wobzala: Takulitsa mgwirizano wamphamvu ndi minda yambiri yachilengedwe. Izi zimatsimikizira kupezeka kosasinthika kwa zosakaniza za premium botanical, zotengedwa mwachindunji kuchokera ku chilengedwe.

2. Malo Opangira M'nyumba: Ndi malo athu apamwamba opangira zinthu, timakhala ndi ulamuliro pa sitepe iliyonse ya kupanga.

3. Mapangidwe Ogwirizana: Pozindikira zosowa zosiyanasiyana za makasitomala athu, timapereka zosankha zosinthira pazowonjezera ndi zolemba.

4. Njira Zotumizira Zomwe Zakhazikitsidwa: Njira yathu yogawira yokhazikitsidwa bwino imatsimikizira kuti kutumiza kwapadziko lonse kwabwino komanso kodalirika. Timayika patsogolo ma CD otetezeka komanso mayendedwe abwino kuti titsimikizire kuti zinthuzo zimafika kwa makasitomala athu zili bwino komanso munthawi yake.

5. Chitsimikizo Chachikulu: Kudzipereka kwathu ku khalidwe labwino kumawonekera kudzera mu certification yathu yonse. Zogulitsa zathu zimakwaniritsa miyezo yolimba yoyesera yamayiko osiyanasiyana ndi mabungwe owongolera, kutsimikizira kudzipereka kwathu kuchita bwino.

Physicochemical Properties

Ufa Woyera wa Luteolin nthawi zambiri amapezeka ngati makristasi achikasu ngati singano. Imawonetsa kukhazikika kwamafuta, sungasinthe m'madzi ozizira, imayankhidwa pang'ono m'madzi otentha, imayankhidwa mosavuta muzotsukira organic ndi zotsatira za alkaline, ndipo zotsatira zake zopanda madzi zimakhala zofooka acidic. Chotsatira chopanda madzi chimapereka utoto wotumbululuka wotumbululuka ndipo ukhoza kusungunuka mu zotsatira 10 za sodium hydroxide, kutembenukira mozama unheroic. Luteolin imakhalabe yokhazikika pamikhalidwe yabwinobwino. Muzomera, luteolin imapezeka mu mawonekedwe a aglycone (molekyu yopanda shuga) ndi glycosides (aglycones womangidwa kumagulu a shuga amodzi kapena angapo).

Zida Zopangira za Luteolin Bulk Powder

Luteolin Bulk ufa imafalitsidwa kwambiri m'chilengedwe. Inapeza dzina lake chifukwa cha kudzipatula koyamba kwa masamba, zimayambira, ndi nthambi za chomera cha herbaceous Reseda odorata L. mu banja la Resedaceae. Zitha kukhala olekanitsidwa zosiyanasiyana zachilengedwe mankhwala azitsamba ndi masamba zipatso. Pakalipano, zapezeka zambiri m'zitsamba zachilengedwe monga honeysuckle, chrysanthemum, mentha, Ajuga decumbus, atitchoku, perilla, Scutellaria baicalensis, ndi Gentiana macrophylla, komanso zipatso zamasamba monga Brussels zikumera, kabichi, kolifulawa. , kabichi, kaloti, udzu winawake, tsabola wa belu, tsabola, ndi mtedza. Zinthu zina monga mafuta a azitona ndi vinyo wofiira, komanso zomera monga Impatiens noli-tangere, thyme, Plantago asiatica, ndi Achyranthes bidentata, zilinso ndi luteolin.

M'zigawo Njira

Njira zotulutsira luteolin zitha kugawika m'magulu awiri: njira zachikhalidwe zochotsa ndi njira zatsopano zochotsera. Yotsirizira akhoza kugawidwa mwachindunji m'zigawo ndi m'zigawo pambuyo zopangira chisanadze processing. Zakale zikuphatikizapo ultrasound-anathandiza m'zigawo, mayikirowevu-anathandiza m'zigawo, supercritical madzimadzi m'zigawo, ndi ayoni madzi-anathandiza m'zigawo. Izi zikuphatikiza kutulutsa kothandizidwa ndi ma enzyme komanso kuphulika kwa nthunzi kusanachitike, ndicholinga chofuna kupeza zokolola zambiri komanso kukhazikika kwa luteolin. Njira zodziwika bwino zodzipatula ndi kuyeretsa luteolin zimaphatikizapo kutulutsa zosungunulira, kuchotsa micelle-mediated, resin adsorption, high-speed countercurrent chromatography, ndi ma molecularly imprinted polymer adsorption. Njira ziwiri zoyambilira ndizoyenera kukulitsa chotsitsacho, pomwe njira zomalizazi zitha kugwiritsidwa ntchito kuti ziyeretsedwenso.

ntchito;

1. Anti-Inflammatory: pakali pano, mphamvu yotsutsa-kutupa ya luteolin imakhulupirira kuti ikugwirizana ndi kuletsa kwa nitric oxide (NO) mankhwala ndi ma cytokines ena osokonezeka omwe ali ngati TNF- α ndi interleukin-6 (IL- 6). Zimakhudzanso kuponderezedwa kwa protein tyrosine phosphorylation ndi gene expression intermediated by nuclear recap factor KB(NF- KB).

2. Anti-Allergic: Luteolin ingalepheretse kutulutsa kwa antipathetic reaction intercessors kuchokera ku IgE- intermediated mortal mast cells, kuphatikizapo histamine, leukotrienes, prostaglandin D2, ndi monocyte macrophage colony- stimulating factor. Zochita zake zitha kulumikizidwa ndi kuletsa kwa calcium affluence ndi protein kinase C (PKC) translocation activation.

3. Anti-Inflammatory Demyelinating Diseases: In vitro, Luteolin ufa imatha kuphimba modalira oligodendrocyte motsutsana ndi kuwonongeka kwa okosijeni komwe kumatsimikiziridwa ndi hydrogen peroxide, kuletsa mwamphamvu mphamvu ya macrophages kupita ku madontho a myelin, kuchepetsa m'badwo wamagulu amitundu ya okosijeni, kutsitsa mawonekedwe a mapuloteni a iNOS, ndi ma boluses otsika, kugwetsa macrophage. - adapanga zinthu za NO.

4. Anti-Fibrosis: Luteolin ikhoza kuchepetsa kuchuluka kwa chiwindi fibrosis, kuchepetsa zochitika za hydroxyproline (HYP) ndi malondialdehyde (MDA) mu thaulo la chiwindi, ndi kupondereza mawu a mtundu wa I procollagen mRNA. Mu vitro, imatha kuletsa kuchulukana ndi kusakanikirana kwa kolajeni kwa maselo a hepatic stellate (HSC). Ikhozanso kuchepetsa kusintha kwa pulmonary fibrosis histopathological chifukwa cha bleomycin, kuchepetsa kulemera kwa mapapu, kuchepetsa kwambiri zochitika za MDA ndi HYP, kulepheretsa kufotokoza kwa transubstantiating kukula factor- beta 1 (TGF- β1) mRNA mu thaulo la m'mapapo, ndi mu vitro, kupondereza. kuchulukitsa ndi kulimbikitsa apoptosis ya kufa embryonic mapapu fibroblasts.

5. Mitsempha ya Mitsempha: Mu vivo, luteolin ikhoza kulepheretsa kubadwa kwa mitsempha ya kalulu ya corneal yomwe imatsimikiziridwa ndi vascular endothelial growth factor (VEGF), ndi in vitro, imalepheretsa kupulumuka ndi kufalikira kwa maselo amtundu wa umbilical tone endothelial cells (HUVECs) otsimikiziridwa ndi VEG. Ikhoza kulepheretsa kwambiri kufalikira ndi kusakanikirana kwa DNA kwa maselo osalala a mitsempha ya mitsempha yomwe imatsimikiziridwa ndi platelet-deduced growth factor-BB (PDGF-BB), kulepheretsa maselo mu gawo la G1, ndipo tcheru-kudalira kuchepetsa kupanikizika kwa mitsempha ya magazi yomwe isanachitike phenylephrine, envenom high-potassium-constriction vasoconstriction, parade arterial vasodilation goods, ndi vasodilation effect yake isnon-endothelium dependent. Sing'anga yake imalumikizidwa ndi kuletsa kwachindunji kwa mayendedwe amagetsi amagetsi, njira za calcium zolandirira, kutulutsidwa kwa calcium m'kati mwa cell, komanso kuyambitsa njira za potaziyamu, ndipo sizidalira α ndi β receptors.

zikalata

Yuantai Organic Bio yadzipereka kupatsa alendo mwayi wapamwamba kwambiri Luteolin Bulk ufa ndi mautumiki kotero kuti wogula aliyense akhoza kusangalala ndi zakudya zachilengedwe, zathanzi, komanso zapamwamba. 

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